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Frequently asked questions

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Are you new to OCTAGAM 10%? Or undergoing treatment and looking for OCTAGAM 10% resources or support? Explore the most commonly asked questions below for more information, including links to additional details and helpful tools.

What is OCTAGAM 10%?

OCTAGAM 10% is a liquid medicine for infusion that contains immunoglobulin G (IgG) and is called intravenous immunoglobulin (IVIg) therapy. It is made from human plasma, which is carefully selected from the blood of healthy donors using strict FDA guidelines to ensure safety.

OCTAGAM 10% is FDA approved to treat dermatomyositis (DM) and chronic immune thrombocytopenia (cITP), which are both conditions in which immunoglobulin therapy has proven to be an effective treatment.

Learn more about OCTAGAM 10%LoadingHow can I save on OCTAGAM 10%?

OCTAGAM offers a co-pay program for eligible patients, as well as support navigating insurance coverage and understanding your financial assistance options through Pfizer IGuideTM. The OCTAGAM Co-Pay Program may help eligible, commercially insured patients pay as little as $0 for OCTAGAM 10%. Additional terms and conditions apply.*

See financial assistance detailsLoadingWhat were the results of the clinical trials of OCTAGAM 10%?

In a clinical trial of adult patients with DM who received OCTAGAM 10%, the majority of patients experienced DM symptom improvement:

  • 79% (37 of 47) of patients treated with OCTAGAM 10% achieved at least minimal improvement vs 44% (21 of 48) with placebo†

†Symptoms were measured on a 100-point scale as measured by the Total Improvement Score (TIS), with 0 being worsening or no improvement and 100 being the most improvement. An improvement of at least 20 points was considered minimal.

View DM results and trial designLoading

In a clinical trial of adult patients with cITP, OCTAGAM 10% helped increase platelets (a type of blood cell) and decrease bleeding:

  • 82% (54 of 66) of patients responded to OCTAGAM 10% with an increase in platelet count within 7 days of treatment
View cITP results and trial designLoadingWhat were the most common side effects seen with OCTAGAM 10%?
  • In a clinical study for adults with DM, the most common drug-related side effects for more than 5% of patients were headache (42%), fever (19%), nausea (16%), vomiting (8%), chills (7%), musculoskeletal pain (7%), and increased blood pressure (6%)
  • In a clinical study for adults with cITP, the most common drug-related side effects for more than 5% of patients were headache (25%), fever (15%), and increased heart rate (11%)
How are OCTAGAM 10% treatments given?

OCTAGAM 10% is given by IV infusion through a needle inserted into your vein. This may be done at home, at an infusion center, or in a hospital, but it is always done by a healthcare professional. Your infusion will start at a slow rate, while your healthcare provider monitors you for signs of infusion reactions. If you tolerate it well, they may gradually increase your infusion rate.

They may slow or stop your infusion depending on your infusion reaction.

Starting OCTAGAM 10%LoadingHow long does it take to infuse OCTAGAM 10%?

Your infusions with OCTAGAM 10% may last several hours and be divided into 2 or more days. The total time depends on your dose and rate of infusion. Some people may have a quicker infusion, while others may need more time.

†The DM example is based on a 160 g total dose for a 176-lb (80-kg) patient and an infusion administration ramp-up rate of 1, 2, and then 4 mg/kg/min. The cITP example is based on a 160 g total dose for a 176-lb (80-kg) patient and an infusion administration ramp-up rate of 1, 2, 4, 8, and then 12 mg/kg/min.

See more infusion infoLoadingHow can I keep track of my OCTAGAM 10% treatments?

It is important to record the details of each OCTAGAM 10% infusion so that your healthcare provider can monitor your progress, which is why Pfizer provides an infusion tracker. Be sure to fill out every section of your infusion tracker and keep an accurate record of each time your OCTAGAM 10% is administered. During your first few infusions, it is recommended that you ask your infusion nurse or trainer to help you complete your tracker.

You can download and print the OCTAGAM Therapy Tracker or download the Ig Companion mobile app to your phone for your convenience.

Get Ig CompanionLoading

Learn more about OCTAGAM 10%

Did you know OCTAGAM 10% is
an IV infusion? See how it’s made
and more

Resources at your fingertips

View downloadable materials and educational videos for patients

Looking for financial assistance?

Learn about the OCTAGAM 10%
Co-Pay Program for eligible
patients

*The OCTAGAM Co-Pay Program provides eligible patients assistance of up to $12,500 per year. Once a patient reaches the annual maximum benefit, patient is responsible for paying the remaining monthly out-of-pocket costs. The OCTAGAM Co-Pay Program is good only in the US and Puerto Rico. No membership fees. Federal and state health care beneficiaries are not eligible. Private insurance only. Eligibility and restrictions apply. See full Terms and Conditions on the Support and financial assistance page.

Patients should always ask their doctors for medical advice about adverse events.
You may report an adverse event related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the US Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where healthcare professionals and consumers can report problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088.
OCTAGAM® is a registered trademark of Octapharma AG.
This site is intended only for US residents. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider.
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